cav3-KO/B6(177), B6-Cav3 KO#177 cav3-KO/B6(177), B6-Cav3 KO#177 Heterozygote x Wild-type [C57BL/6JJcl] Cav3 (Caveolin 3) gene knockout mice. Cav3 is a muscle-specific form of the caveolin family proteins, which are small molecular weight proteins shown to be associated with the caveolar plasma membrane. Homozygous mutant mice show mid myopathic changes in muscle from 8 weeks ages. Viable and fertile. Line 177 (C57BL/6 background) (RBRC02374), Line 32 (mixed background) (RBRC02375), Line 142 (mixed background), Line 177 (mixed background) (RBRC02377). mouse phosphoglycerate kinase promoter (PGK promoter), E coli neo, mouse caveolin-3(Cav3) genomic DNA C (3-6 months) RBRC02374 条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Hum. Mol. Genet., 9, 3047-3054 (2000).<br>利用者は、研究成果の公表にあたって、笹岡俊邦博士へ謝辞の表明を必要とする。利用者が本件リソースを使用して得られた研究成果に基づき特許等の申請、及び事業活動を行う場合は、寄託者と別途協議を行う。 Cav3 (caveolin 3) 遺伝子のノックアウトマウス。ホモマウスは生存性、妊性あり。ライン177 (B6背景) (RBRC02374) 、ライン32 (混合背景) (RBRC02375) 、ライン142 (混合背景) (RBRC02376) 、ライン177 (混合背景) (RBRC02377) 。, Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> Toshikuni SASAOKA 笹岡　俊邦 true In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Hum. Mol. Genet., 9, 3047-3054 (2000).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Toshikuni Sasaoka is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. Developed by Toshikuni Sasaoka, National Institutes of Natural Sciences (National Institute of Neuroscience, National Center of Neurology and Psychiatry). C（3〜6か月） Cav3 (caveolin 3) 遺伝子のノックアウトマウス。ホモマウスは生存性、妊性あり。ライン177 (B6背景) (RBRC02374) 、ライン32 (混合背景) (RBRC02375) 、ライン142 (混合背景) (RBRC02376) 、ライン177 (混合背景) (RBRC02377) 。 B6.129S4-Cav3<tm1Ncnp>/177 B6.129S4-Cav3<tm1Ncnp>/177 戻し交配後の兄妹交配 Background系統：C57BL/6J J1 [129S4/SvJae] 戻し交配後の兄妹交配Background系統：C57BL/6J 基礎生物学研究所（国立精神・神経医療研究センター神経研究所）・笹岡俊邦。 <a href='https://brc.riken.jp/mus/pcr02374'>Genotyping protocol -PCR-</a>